Retatrutide is a synthetic peptide made up of 39 amino acids. It is a triple receptor agonist, or tri-agonist, meaning it activates the GLP-1, GIP and glucagon receptors. Each of these receptors plays a different role in hormone signaling and the regulation of metabolism.
Researchers study retatrutide to better understand how these three pathways work together to regulate blood sugar, appetite and energy use. Its activity is also of interest in research into insulin resistance and how cells respond to insulin.
Technical details
| Formula | C221H342N46O68 |
|---|---|
| Molecular weight | 4731.3 g/mol |
| CAS | 2381089-83-2 |
| Form | Freeze-dried powder, 10 mg per vial |
| Research to date | Extensive published literature |
Lab certificate
Tested by Freedom Diagnostics: identity confirmed by LC-MS, purity 99.76% by HPLC (accession 2609080735, reported 9 September 2026).
Storage
Store the sealed vial in a freezer at around -20 °C, away from light and moisture.
For laboratory research use only. Not for human or veterinary use, and not for diagnostic or therapeutic purposes.



